Microbiota Research and Therapeutics
Advancing the therapeutic use of intestinal microbiota
Congratulations to Dr. Khoruts (with the support of his research team) for making the 2020 Highly Cited Researchers list! This distinguished international list recognizes researchers whose citation records place them in the top 1 percent of citation counts for field and publication year.
A recent BBC article highlighted our program and the media’s favorite doctor and patient-turned-research program manager team of Dr. Khoruts and Amanda Kabage.
What we do
Develop effective and practical restorative microbiota therapies and
discover novel strategies to nurture and maintain healthy microbiota.
Our program pioneered the use of IMT to restore intestinal health
and created the first stool donor program worldwide.
Intestinal Microbiota Transplants and CDI
IMT success rate
IMT capsules produced
Cost to Patients
Our Partnership With Achieving Cures Together
Achieving Cures Together is a nonprofit organization started by University of Minnesota alumnus Peter Westerhaus during his college term at Carlson School of Management. This organization raises funds specific to our program via marathon sponsorships and other events. Visit the Achieving Cures Together website for more information.
Gut Microbiome Health
We are currently recruiting patients with ulcerative colitis for an intestinal microbiota transplant clinical research study.
The U.S. Department of Veterans Affairs is studying the efficacy of IMT for the prevention of recurrent C. difficile infection (CDI) after treatment of recurrent CDI with standard antimicrobial therapy.
Studying the effects of intestinal microbiota transplant in veterans with cirrhosis.
Intestinal microbiota transplants for children with Pitts Hopkins Syndrome and gastrointestinal disorders.
The University of Minnesota Masonic Cancer Center is recruiting patients for an IMT clinical trial to understand the clinical efficacy of IMT treatment for patients with acute myeloid leukemia and patients receiving allogenic hematopoietic stem cell transplants.
Intestinal microbiota transplant for children with autism spectrum disorder who have gastrointestinal disorders.
Our Research Team
The intestinal microbiota research and therapeutics team is led by Dr. Alexander Khoruts, Professor of Medicine, Division of Gastroenterology, Hepatology and Nutrition at the University of Minnesota. The team is comprised of world class U of MN faculty and staff who bring passion and diverse skill sets to the clinical care setting and to the lab bench.
FMT or IMT: That is the Question
In 2010, a group of physicians published recommendations on how to perform a microbiota transplant. At that time, they decided upon the term Fecal Microbiota Transplant. As the years passed, the phrase began to be abbreviated to Fecal Transplant. Concerned about the negative connotation of this term, Dr. Khoruts teamed up with Dr. Brandt to pave a path toward the use of Intestinal Microbiota Transplantation (IMT) instead.