Microbiota

Therapeutics

in the News

Gut check on cancer

Cracking the mysteries of the human microbiome—those teeming communities of bacteria, fungi, and viruses that live on and within each of us—remains one of medicine’s most exciting frontiers.

Dr. Alex Khoruts discusses "Reseeding the Gut"

In the December 2016 Nature Outlook article entitled “Reseeding the Gut” Dr. Alexander Khoruts discusses how gut microbiota likely plays important roles in inflammatory bowel disease.

CFI's Alex Khoruts is quoted by NBC News

As the number of transplants increased so did the methods of delivery.  Today the debate is whether or not to designate the FMT as an investigational drug or to continue with the FMTs as organ transplants.

Drug Companies and Doctors Battle Over the Future of Fecal Transplants

There’s a new war raging in health care, with hundreds of millions of dollars at stake and thousands of lives in the balance.

Mysteries of the Microbiome

Dr. Alexander Khoruts understands if you hesitate to shake his hand. He does dirty work. But he’s saving lives with what the rest of us flush away.

There were no guidelines for fecal transplants. Then, a patient died.

In June, after a patient died and another was sickened from a fecal transplant that contained drug-resistant bacteria, the Food and Drug Administration stepped in and set new guidelines for the procedure.

A clinician's guide to microbiome testing

The intestinal microbiota, also commonly known as the ‘‘gut microbiome’’ is integral to human physiology and has wide-ranging effects on the development and function of the immune system, energy metabolism and even nervous system activity.

Gut Feeling

Patient-turned-researcher teams up with her doctor to advance U of M’s pioneering microbiota transplant program.

How sun exposure can affect your microbiome

On the surface, sunlight and gut microbes seem to have nothing in common — after all, your gut bacteria are unlikely to find themselves catching some rays.

Fecal transplants work better than antibiotics to treat deadly bacterial infection

The new study is the first to look at the treatment’s effects on complications that can stem from the infection.

Fecal Microbiota Transplantation: An Interview with Alex Khoruts

A new, highly active sector of therapeutics in the form of fecal microbiota transplantation (FMT) has emerged in the last several years based on novel paradigms in medicine that are challenging to the regulators such as the US Food and Drug Administration (FDA).

Minnesota faces challenge in halting deadly colon infection's spread

For years, a bacteria known as Clostridium difficile that can cause intestinal infections, crippling diarrhea and even death was thought to be a problem confined to hospitals and care facilities.

FDA hears testimony on enforcement discretion of FMT for C. diff

The FDA held a public comment session on Monday in Washington, D.C., to hear testimony on the agency’s policy on enforcement discretion of fecal microbiota transplantation for patients with recurrent Clostridioides difficile infection, as well as what is needed to make a path forward to approval.

How Microbes Defend and Define Us

Dr. Alexander Khoruts had run out of options. In 2008, Dr. Khoruts, a gastroenterologist at the University of Minnesota, took on a patient suffering from a vicious gut infection of Clostridium difficile.

Minnesota researchers help unlock 'gut science' cures

The Twin Cities is emerging as a major player in what could become a multibillion dollar industry: Gut science.

Excerpt from Gulp: Adventure on the Alimentary Canal by Mary Roach

It’s tough to find an inappropriate mealtime conversation with this group – not because they’re crass or ill-mannered, but because they view the universe of the colon very differently from the rest of us.

Online Video of Evolving Human Microbiome Lecture Now Available

On February 17, Alexander Khoruts, MD, of the University of Minnesota’s Microbiota Therapeutics Program delivered the first lecture in the three-part Consortium-sponsored microbiome series.

Inside Your Health

When someone is feeling terribly sick and nothing seems to be working, most people will do just about anything for relief. 

Hand Photo by Mark Fletcher-Brown on Unsplash

Scientist at microscope Photo by National Cancer Institute on Unsplash

Reagents Photo by National Cancer Institute on Unsplash

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Computer Photo by Scott Graham on Unsplash

Microscope Photo by Ousa Chea on Unsplash

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