Publications

Khoruts A, Dicksved J, Jansson JK, Sadowsky MJ.
Changes in the composition of the human fecal microbiome after bacteriotherapy for recurrent Clostridium difficile-associated diarrhea.
Journal of Clinical Gastroenterology. 2010;44(5):354-60. doi: 10.1097/MCG.0b013e3181c87e02

Khoruts A, Sadowsky MJ.
Therapeutic transplantation of the distal gut microbiota.
Mucosal Immunology. 2011;4(1):4-7. doi: 10.1038/mi.2010.79. Epub 2010 Dec 8.

Bakken JS, Borody T, Brandt LJ, et al.
Treating Clostridium difficile infection with fecal microbiota transplantation.
Clinical Gastroenterology and Hepatology. 2011;9(12):1044-9. doi: 10.1016/j.cgh.2011.08.014. Epub 2011 Aug 24. Review.

Borody TJ, Khoruts A.
Fecal microbiota transplantation and emerging applications.
Nature Reviews Gastroenterology & Hepatology. 2012;9(2):88-96. doi: 10.1038/nrgastro.2011.244. Review.

Hamilton MJ, Weingarden AR, Sadowsky MJ, Khoruts A.
Standardized frozen preparation for transplantation of fecal microbiota for recurrent Clostridium difficile infection.
The American Journal of Gastroenterology. 2012;107(5):761-7. doi: 10.1038/ajg.2011.482. Epub 2012 Jan 31.

Weingarden AR, Hamilton MJ, Sadowsky MJ, Khoruts A.
Resolution of severe Clostridium difficile infection following sequential fecal microbiota transplantation.
Journal of Clinical Gastroenterology. 2013;47(8):735-737. doi: 10.1097/MCG.0b013e31829004ae

Hamilton MJ, Weingarden AR, Unno T, Khoruts A, Sadowsky MJ.
High-throughput DNA sequence analysis reveals stable engraftment of gut microbiota following transplantation of previously frozen fecal bacteria.
Gut Microbes. 2013;4(2):125-35. doi: 10.4161/gmic.23571. Epub 2013 Jan 18.

Petrof EO, Khoruts A.
From stool transplants to next-generation microbiota therapeutics.
Gastroenterology. 2014;146(6):1573-1582. doi: 10.1053/j.gastro.2014.01.004

Kelly CR, Ihunnah C, Fischer M, et al.
Fecal microbiota transplant for treatment of Clostridium difficile infection in immunocompromised patients.
The American Journal of Gastroenterology. 2014;109(7):1065-71. doi: 10.1038/ajg.2014.133. Epub 2014 Jun 3.

Khoruts, A.
Faecal microbiota transplantation in 2013: developing human gut microbiota as a class of therapeutics.
Nature Reviews Gastroenterology & Hepatology. 2014;11(2):79-80. doi: 10.1038/nrgastro.2013.231. Epub 2013 Dec 3. Review.

Khoruts A, Weingarden AR.
Emergence of fecal microbiota transplantation as an approach to repair disrupted microbial gut ecology.
Immunology Letters. 2014;162(2):77-81. doi: 10.1016/j.imlet.2014.07.016. Review.

Weingarden AR, Chen C, Bobr A, et al.
Microbiota transplantation restores normal fecal bile acid composition in recurrent Clostridium difficile infection.
American Journal of Physiology – Gastrointestinal and Liver Physiology. 2014;306(4):G310-G319. doi: 10.1152/ajpgi.00282.2013

Shankar V, Hamilton MJ, Khoruts A, et al.
Species and genus level reslution analysis of gut microbiota in Clostridium difficile patients following fecal microbiota transplantation.
Microbiome. 2014;2(13). doi: 10.1186/2049-2618-2-13

Weingarden A, González A, Vázquez-Baeza Y, et al.
Dynamic changes in short- and long-term bacterial composition following fecal microbiota transplantation for recurrent Clostridium difficile infection.
Microbiome. 2015;3(10). doi: 10.1186/s40168-015-0070-0

Kelly CR, Khoruts A, Staley C, et al.
Effect of fecal microbiota transplantation on recurrence in multiply recurrent Clostridium difficile infection.
Annals of Internal Medicine. 2016;165(9):609-616. doi: 10.7326/M16-0271

Khoruts A, Rank KM, Newman KM, et al.
Inflammatory bowel disease affects the outcome of fecal microbiota transplantation for recurrent Clostridium difficile infection.
Clinical Gastroenterology and Hepatology. 2016;14(10):1433-1438. doi: 10.1016/j.cgh.2016.02.018

Weingarden AR, Dosa PI, DeWinter ES, et al.
Changes in colonic bile acid composition following fecal microbiota transplantion are suffficient to control Clostridium difficile germination and growth.
PLOS ONE. 2016. doi: 10.1371/journal.pone.0147210

Staley C, Hamilton MJ, Vaughn BP, et al.
Successful resolution of recurrent Clostridium difficile infection using freeze-dried, encapsulated fecal microbiota; pragmatic cohort study.
The American Journal of Gastroenterology. 2017;112(6):940–947. doi: 10.1038/ajg.2017.6

Staley C, Khoruts A, Sadowsky MJ.
Contemporary applications of fecal microbiota transplantation to treat intestinal diseases in humans.
Archives of Medical Research. 2017;48(8):766-773. doi: 10.1016/j.arcmed.2017.11.006. Review. (link to abstract only)

Khanna S, Vazquez-Baeza Y, González A, et al.
Changes in microbial ecology after fecal microbiota transplantation for recurrent C. difficile infection affected by underlying inflammatory bowel disease.
Microbiome. 2017;5(55). doi: 10.1186/s40168-017-0269-3
Kang D, Adams JB, Gregory AC, et al.
Microbiota transfer therapy alters gut ecosystem and improves gastrointestinal and autism symptoms: an open-label study.
Microbiome. 2017;5(10). doi: 10.1186/s40168-016-0225-7

Newman KM, Rank KM, Vaughn BP, Khoruts A.
Treatment of recurrent Clostridium difficile infection using fecal microbiota transplantation in patients with inflammatory bowel disease.
Gut Microbes. 2017;8(3): 303–309. doi: 10.1016/s0016-5085(17)31409-9

Staley C, Vaughn BP, Graiziger CT, et al.
Community dynamics drive punctuated engraftment of the fecal microbiome following transplantation using freeze-dried, encapsulated fecal microbiota.
Gut Microbes. 2017;8(3):276-288. doi: 10.1080/19490976.2017.1299310

Smillie CS, Sauk J, Gevers D, et al.
Strain tracking reveals the determinants of bacterial engraftment in the human gut following fecal microbiota transplantation.
Cell Host & Microbe. 2018;23(2):229-240. doi: 10.1016/j.chom.2018.01.003

Luca F, Kupfer SS, Knights D, Khoruts A, Blekhman, R.
Functional genomics of host-microbiome interactions in humans.
Trends in Genetics. 2018;34(1):30-40. doi: 10.1016/j.tig.2017.10.001 (link to abstract only)

Vaughn BP, Kaiser T, Staley C, et al.
A pilot study of fecal bile acid and microbiota profiles in inflammatory bowel disease and primary sclerosing cholangitis.
Clinical and Experimental Gastroenterology. 2019;12:9-19. doi: 10.2147/CEG.S186097
Adams JB, Borody TJ, Kang DW, Khoruts A, Krajmalnik-Brown R, Sadowsky MJ.
Microbiota transplant therapy and autism: lessons for the clinic.
Expert Review of Gastroenterology & Hepatology. 2019;13(11):1033-1037. doi: 10.1080/17474124.2019.1687293 (link to abstract only)
Thenappan T, Khoruts A, Chen Y, Weir EK.
Can intestinal microbiota and circulating microbial products contribute to pulmonary arterial hypertension?
American Journal of Physiology: Heart and Circulatory Physiology. 2019;317(5):H1093-H1101. doi: 10.1152/ajpheart.00416.2019 (link to abstract only)
Teigen LM, Geng Z, Sadowsky MJ, Vaughn BP, Hamilton MJ, Khoruts A.
Dietary factors in sulfur metabolism and pathogenesis of ulcerative colitis.
Nutrients. 2019;11(4):931. doi: 10.3390/nu11040931
Vaughn BP, Rank KM, Khoruts A.
Fecal microbiota transplantation: current status in treatment of GI and liver disease.
Clinical Gastroenterology and Hepatology. 2019;17(2):353-361. doi: 10.1016/j.cgh.2018.07.026 (link to abstract only)

Khoruts A, Brandt LJ.
Fecal microbiota transplant: a rose by any other name.
The American Journal of Gastroenterology. 2019;114(7):1176. doi: 10.14309/ajg.0000000000000286

Khoruts A, Hoffmann DE, Palumbo FB.
The impact of regulatory policies on the future of fecal microbiota transplantation.
The Journal of Law, Medicine & Ethics. 2019;47(4):482-504. doi: 10.1177/1073110519897726 (link to abstract only)

Staley C, Kaiser T, Vaughn BP, et al.
Durable long-term bacterial engraftment following encapsulated fecal microbiota transplantaion to treat Clostridium difficile Infection.
mBio. 2019;10(4) e01586-19. doi: 10.1128/mBio.01586-19

Jahansouz C, Staley C, Kizy S, et al.
Antibiotic-induced disruption of intestinal microbiota contributes to failure of vertical sleeve gastrectomy.
Annals of Surgery. 2019;269(6):1092-1100. doi: 10.1097/SLA.0000000000002729 (link to abstract only)

Dostal Webster A, Staley C, Hamilton MJ, et al.
Influence of short-term changes in dietary sulfur on the relative abundances of intestinal sulfate-reducing bacteria.
Gut Microbes. 2019;10(4):447-457. doi: 10.1080/19490976.2018.1559682

Bajaj JS, Khoruts A.
Microbiota changes and intestinal microbiota transplantation in liver diseases and cirrhosis.
Journal of Hepatology. 2020;72(5):P1003-1027. doi: 10.1016/j.jhep.2020.01.017

Teigen L, Mathai PP, Matson M, et al.
Methanogen abundance thresholds capable of differentiating in vitro methane production in human stool samples.
Digestive Diseases and Sciences. 2020. doi: 10.1007/s10620-020-06721-5 (link to abstract only)

Rashidi A, Kaiser T, Graiziger C, et al.
Specific gut microbiota changes heralding bloodstream infection and neutropenic fever during intensive chemotherapy.
Leukemia. 2020;34(1):312-316. doi: 10.1038/s41375-019-0547-0 (no open access link available)

Khoruts A.
Can FMT Cause or Prevent CRC? Maybe, But There Is More to Consider.
Gastroenterology. 2021; ISSN 0016-5085. doi: 10.1053/j.gastro.2021.06.074.

Staley C, Halaweish H, Graiziger C, et al.
Lower endoscopic delivery of freeze-dried intestinal microbiota results in more rapid and efficient engraftment than oral administration.
Sci Rep. 2021 Feb 25;11(1):4519. doi: 10.1038/s41598-021-84152-6.

Khoruts A, Staley C, and Sadowsky MJ.
Faecal microbiota transplantation for Clostridioides difficile: mechanisms and pharmacology.
Nat Rev Gastroenterol Hepatol. 2021;18:67-80. doi: 10.1038/s41575-020-0350-4. (link to abstract only)

Rashidi A, Ebadi M, Rehman TU, et al.
Gut microbiota response to antibiotics is personalized and depends on baseline microbiota.
Microbiome. 2021;9(211). doi: 10.1186/s40168-021-01170-2

Britton RA, Hoffmann DE, Khoruts A.
Probiotics and the Microbiome-How Can We Help Patients Make Sense of Probiotics?
Gastroenterology. 2021;160(2):614-623. doi: 10.1053/j.gastro.2020.11.047. (link to abstract only)

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