Matt Hamilton joined the Microbiota Research and Therapeutics team in 2009, after finishing his PhD in microbial ecology. As a post-doc, he developed protocols to separate and cryopreserve microbiota from stool. These protocols have been adapted and used throughout the world. Matt went on to develop additional protocols for freeze-drying and encapsulating the microbiota, as well as establishing current Good Manufacturing Practice standard operating procedures used by the production team. Matt currently oversees the GMP production of therapeutic microbiota and analyzes microbiome sequence data.
In his spare time Matt enjoys outdoor pursuits including yard work, birling, and urban foraging.
Intestinal microbiota slurry
Lyophilized donor material to be encapsulated
Always lots of dishes to be done
- Hamilton MJ, Weingarden AR, Sadowsky MJ, Khoruts A. Standardized frozen preparation for transplantation of fecal microbiota for recurrent Clostridium difficile infection. Am J Gastroenterol 2012; 107:761-7.
- Staley C, Hamilton MJ, Vaughn BP, Graiziger CT, Newman KM, Kabage AJ, et al. Successful resolution of recurrent Clostridium difficile infection using freeze-dried, encapsulated fecal microbiota; pragmatic cohort study. Am J Gastroenterol 2017.